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Tried everything, been on Protonix for 5 years. I can now eat anything as spicy and as hot as I like, and do not have acid reflux.

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The geometric mean AUC estimated from population PK analysis after a 40 mg PROTONIX tablet in pediatric patients was about 39% and 10% higher respectively in 6 to 11 and 12 to 16 year-old children, compared to that of adults (Table 6).

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Because clopidogrel is an inactive product that has to be converted to its active metabolite in order to be effective, there is considerable concern that some PPIs may reduce or block this conversion and, thereby, reduce the effect of clopidogrel.

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